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Apigenin sensitizes radiotherapy of mouse subcutaneous glioma through attenuations of cell stemness and DNA damage repair by inhibiting NF-κB/HIF-1α-mediated glycolysis

Changhao Jia, Ying Zhao, Hui Huang, Ke Fan, Tao Xie, Mei-Lin Xie

2022The Journal of Nutritional Biochemistry25 citationsDOI

Topics & Concepts

ApigeninGliomaCancer researchNF-κBChemistryRadioresistancePKM2Lactate dehydrogenaseMolecular biologyGlycolysisBiologyBiochemistryPyruvate kinaseMedicineRadiation therapyEnzymeInternal medicineSignal transductionFlavonoidAntioxidantCancer, Hypoxia, and MetabolismFlavonoids in Medical ResearchAutophagy in Disease and Therapy
Apigenin sensitizes radiotherapy of mouse subcutaneous glioma through attenuations of cell stemness and DNA damage repair by inhibiting NF-κB/HIF-1α-mediated glycolysis | Litcius