Engineering a deformation-free plastic spiral inertial microfluidic system for CHO cell clarification in biomanufacturing
Hyungkook Jeon, Taehong Kwon, Junghyo Yoon, Jongyoon Han
Abstract
). Benefitting from the continuous and clogging-free separation with an industry-level throughput, the cell clarification device could be a critical breakthrough for the production of therapeutic biologics such as antibodies or vaccines, impacting biomanufacturing in general.
Topics & Concepts
MicrofluidicsBiomanufacturingMaterials sciencePolydimethylsiloxaneThroughputSpiral (railway)Deformation (meteorology)NanotechnologyBiomedical engineeringMechanical engineeringComposite materialComputer scienceEngineeringGeneticsBiologyTelecommunicationsWirelessMicrofluidic and Bio-sensing TechnologiesMicrofluidic and Capillary Electrophoresis Applications3D Printing in Biomedical Research