Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways
Emad H. M. Hassanein, Esam Omar Kamel, Fares E.M. Ali, Marwa A. Ahmed
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BOxidative stressPharmacologyChemistryBerberineMethotrexateSignal transductionToxicityMedicineInternal medicineBiochemistryOrganic chemistryChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchDrug-Induced Hepatotoxicity and Protection