<sup>19</sup>F Electron-Nuclear Double Resonance Reveals Interaction between Redox-Active Tyrosines across the α/β Interface of <i>E. coli</i> Ribonucleotide Reductase
Andreas Meyer, Annemarie Kehl, Chang Cui, Fehmke A. K. Reichardt, Fabian Hecker, Lisa-Marie Funk, Manas K. Ghosh, Kuan‐Ting Pan, Henning Urlaub, Kai Tittmann, JoAnne Stubbe, Marina Bennati
Abstract
. The results highlight the important role of state-of-the-art EPR spectroscopy to decipher this mechanism.
Topics & Concepts
Ribonucleotide reductaseChemistryElectron nuclear double resonanceElectron paramagnetic resonanceElectron transferRibonucleotideDeoxyribonucleotidesCrystallographyResonance (particle physics)StereochemistryElectron acceptorCofactorPulsed EPRAcceptorMutantElectron transport chainPhotochemistryNucleotideEnzymeNuclear magnetic resonanceBiochemistryAtomic physicsProtein subunitRadiologyCondensed matter physicsMedicinePhysicsGeneMagnetic resonance imagingSpin echoElectron Spin Resonance StudiesMetal-Catalyzed Oxygenation MechanismsLanthanide and Transition Metal Complexes