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Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing

Tsion Abay, Robert R. Stickels, Meril Takizawa, Benan N. Nalbant, Yu-Hsin Hsieh, Sidney Hwang, Catherine Snopkowski, Kenny Yu, Zaki Abou-Mrad, Viviane Tabar, Brooke E. Howitt, Leif S. Ludwig, Ronan Chaligné, Ansuman T. Satpathy, Caleb A. Lareau

2025Nature Genetics22 citationsDOIOpen Access PDF

Topics & Concepts

BiologyRNAComputational biologyCellSingle-cell analysisCell sortingSingle cell sequencingGenomicsGeneticsMolecular biologyPhenotypeGenomeGeneExome sequencingSingle-cell and spatial transcriptomicsExtracellular vesicles in diseaseImmune cells in cancer
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing | Litcius