Ultra-sensitive and specificity quantitative detection of miRNA using a combined CRISPR/Cas13a and DNA-PAINT
Ziyue Xu, Liwen Guan, Jiawei Peng, Shuangyi Huang, Ting Liu, Ting Xiong, Yifei Yang, Xiaolei Wang, Xian Hao
Topics & Concepts
Trans-activating crRNACRISPRComputational biologymicroRNADNABiologyNanotechnologyGeneticsGenome editingMaterials scienceGeneAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryCRISPR and Genetic Engineering