Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
Qingzhu Shi, Qicong Shen, Yanfang Liu, Yang Shi, Wenwen Huang, Xi Wang, Zhiqing Li, Yangyang Chai, Hao Wang, Xiangjia Hu, Nan Li, Qian Zhang, Xuetao Cao
Topics & Concepts
Cathepsin BTumor microenvironmentCancer researchLysosomeCathepsinMetastasisCancer cellCancerBiologyCathepsin LChemistryBiochemistryEnzymeTumor cellsGeneticsImmune cells in cancerAutophagy in Disease and TherapyGlycosylation and Glycoproteins Research