Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations
Mahmoud S. Elkotamy, Mohamed K. Elgohary, Sara T. Al‐Rashood, Hadia Almahli, Wagdy M. Eldehna, Hatem A. Abdel‐Aziz
Topics & Concepts
ChemistryThiazolePyridineStereochemistryIn vitroCombinatorial chemistryInducerInhibitory postsynaptic potentialBiochemistryMedicinal chemistryGeneBiologyNeuroscienceSynthesis and biological activityCancer Mechanisms and TherapyHER2/EGFR in Cancer Research