SH3- and actin-binding domains connect ADNP and SHANK3, revealing a fundamental shared mechanism underlying autism
Yanina Ivashko‐Pachima, Maram Ganaiem, Inbar Ben-Horin-Hazak, Alexandra Lobyntseva, Naomi Bellaiche, Inbar Fischer, Gilad Levy, Shlomo Sragovich, Gidon Karmon, Eliezer Giladi, Shula Shazman, Boaz Barak, Illana Gozes
Topics & Concepts
BiologyAnkyrin repeatSH3 domainBinding siteNapCell biologyPlasma protein bindingGeneticsMolecular biologyProto-oncogene tyrosine-protein kinase SrcSignal transductionGeneNeurosciencePeptidase Inhibition and AnalysisSignaling Pathways in DiseaseGenetics and Neurodevelopmental Disorders