Litcius/Paper detail

Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome

Joleen Grandt, Ingo Gottschalk, Annegret Geipel, U. Gembruch, Corinna Simonini, Eva Weber, Christoph Berg, Andreas Müller, Brigitte Strizek

2022Journal of Clinical Medicine19 citationsDOIOpen Access PDF

Abstract

(1) Background: Severe fetal hydrothorax can be treated by intrauterine thoracoamniotic shunting (TAS). The aim of this study was to assess perinatal outcome and complication rates of TAS with a novel Somatex intrauterine shunt. (2) Methods: This is a single-center retrospective study of all fetuses with hydrothorax treated with TAS using a Somatex shunt between 2014 and 2020. (3) Results: A total of 39 fetuses were included in the study. Mean gestational age at first intervention was 27.4 weeks (range 19–33). Of these, 51% (n = 20) of fetuses had fetal hydrops, which resolved in 65% (13/20) before delivery. The live birth rate was 97% (n = 38), and 74% (n = 29) survived the neonatal period. The rate of postnatal pulmonary complications was high, with 88% of neonates requiring any kind of ventilatory support. There were 23% (n = 9) genetic abnormalities (trisomy 21 and Noonan syndrome). (4) Conclusions: TAS with a Somatex shunt has a high technical success rate, leading to high neonatal survival rates. Pregnancy and neonatal outcome is comparable to TAS for fetal hydrothorax using different shunt types.

Topics & Concepts

MedicineHydrothoraxFetusObstetricsGestational ageTrisomyPregnancyPulmonary hypoplasiaComplicationRetrospective cohort studySurgeryAscitesGeneticsBiologyCongenital Diaphragmatic Hernia StudiesLymphatic Disorders and TreatmentsPleural and Pulmonary Diseases