The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches
Alice Drobny, Susy Prieto Huarcaya, Jan Philipp Dobert, Annika Kluge, Josina Bunk, Theresia Schlothauer, Friederike Zunke
Topics & Concepts
NeurodegenerationLysosomeAutophagyCathepsinBiologyHuntingtinHuntington's diseaseCell biologyNeuronal ceroid lipofuscinosisCathepsin DNeuroscienceDiseaseMedicineBiochemistryPathologyEnzymeGeneApoptosisLysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and TreatmentsCellular transport and secretion