The Swedish dilemma - the almost exclusive use of APPswe-based mouse models impedes adequate evaluation of alternative β-secretases
Fred Armbrust, Kira Bickenbach, Liana Marengo, Claus U. Pietrzik, Christoph Becker‐Pauly
Topics & Concepts
Amyloid precursor protein secretaseAmyloid precursor proteinProteasesPathogenesisCathepsinCathepsin DNeuroscienceDementiaAlzheimer's diseaseChemistryBiologyCell biologyMedicineDiseaseBiochemistryInternal medicineEnzymeAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesPrion Diseases and Protein Misfolding