The Transient Receptor Potential Vanilloid Type 2 (TRPV2) Channel–A New Druggable Ca2+ Pathway in Red Cells, Implications for Red Cell Ion Homeostasis
Stéphane Égée, Lars Kaestner
Abstract
with the channels agonists 9-THC and CBD, but the authors found in agreement with previous investigations (Chari-Bitron and Shahar, 1979) a cell swelling/overhydration. The explanation of this effect remains completely elusive, although we propose an initial concept of a mechanism (see below:
Topics & Concepts
Transient receptor potential channelDruggabilityTRPVIon channelReceptorTRPM2ChemistryCell biologyHomeostasisRed CellMedicineTRPV1BiochemistryBiologyInternal medicineGeneErythrocyte Function and PathophysiologyIon Channels and ReceptorsNeonatal Health and Biochemistry