The IBD-disk Is a Reliable Tool to Assess the Daily-life Burden of Patients with Inflammatory Bowel Disease
Sara Tadbiri, Maria Nachury, Yoram Bouhnik, Mélanie Serrero, Xavier Hébuterne, Xavier Roblin, Julien Kirchgesner, Guillaume Bouguen, Denis Franchimont, Guillaume Savoye, Anthony Buisson, Édouard Louis, Stéphane Nancey, Véred Abitbol, Jean‐Marie Reimund, Olivier Dewit, Lucine Vuitton, Nicolas Matthieu, Laurent Peyrin‐Biroulet, Cyrielle Gilletta, Matthieu Allez, S Viennot, Caroline Trang-Poisson, Nina Dib, Hédia Brixi, Médina Boualit, Laurianne Plastaras, Lucile Boivineau, Mathurin Fuméry, Ludovic Caillo, David Laharie, Aurélien Amiot, GETAID-IBD-disk study group, Aurélien Amiot, Sara Tadbiri, Charlotte Gagnière, Jenny Tannoury, Maria Nachury, Benjamin Pariente, Pauline Wils, Yoram Bouhnik, Carmen Stefănescu, Xavier Tréton, Mélanie Serrero, Jérôme Filippi, Xavier Hébuterne, Nadia Arab, Virginie Cluzeau, Xavier Roblin, Émilie Del Tedesco, Laurent Beaugerie, Philippe Seksik, Anne Bourrier, Cecilia Landmann, Julien Kirchgesner, Harry Sokol, Guillaume Bouguen, Laurent Siproudhis, Marie DeWit, Denis Franchimont, Guillaume Savoye, Anthony Buisson, Edouard Louis, Cathérine Reenaers, Stephane Nancey, Gilles Boschetti, Claire Gay, Pauline Danion, Bernard Flourié, Véred Abitbol, Georgia Malamut, Jean‐Marie Reimund, Bénédicte Caron, Olivier Dewit, Lucine Vuitton, Nicolas Mathieu, Sandie Pestour, Laurent Peyrin‐Biroulet, Camille Zallot, Cyrielle Gilletta, Matthieu Allez, Jean-Marc Gornet, Clotilde Baudry, S Viennot, Arnaud Bourreille, Caroline Trang-Poisson, Nina Dib, Hedi Brixi, Guillaume Cadiot, Medina Boualit, Claire Painchart, Laurianne Plastaras, Lucile Boivineau, Romain Altwegg, Mathurin Fuméry, Ludovic Caillo, David Laharie, Pauline Rivière, Florian Poullenot, Benoît Coffin
Abstract
BACKGROUND AND AIM: The inflammatory bowel disease [IBD]-disk is a 10-item self-questionnaire that is used to assess IBD-related disability. The aim of the present study was to evaluate this tool in the assessment of IBD daily-life burden. METHODS: A 1-week cross-sectional study was conducted in 42 centres affiliated in France and Belgium. Patients were asked to complete the IBD-disk [best score: 0, worst score: 100] and a visual analogue scale [VAS] of IBD daily-life burden [best score: 0, worst score: 10]. Analyses included internal consistency, correlation analysis, and diagnostic performance assessment. RESULTS: Among the 2011 IBD outpatients who responded to the survey [67.8% of the patients had Crohn's disease], 49.9% were in clinical remission. The IBD-disk completion rate was 73.8%. The final analysis was conducted in this population [n = 1455 patients]. The mean IBD-disk score and IBD daily-life burden VAS were 39.0 ± 23.2 and 5.2 ± 2.9, respectively. The IBD-disk score was well correlated with the IBD daily-life burden VAS [r = 0.67; p <0.001]. At an optimal IBD-disk cut-off of 40, the area under the receiver operating characteristic curve [AUROC] for high IBD daily-life burden [VAS >5] was 0.81 (95% confidence interval [CI]: 0.79-0.83; p <0.001). CONCLUSIONS: In a large cohort of patients, the IBD-disk score was well correlated with IBD daily-life burden, and it could be used in clinical practice.