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Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance

Sepideh Mirzaei, Aliasghar Tabatabaei Mohammadi, Mohammad Gholami, Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Kiavash Hushmandi, Pooyan Makvandi, Marek Samec, Alena Líšková, Peter Kubatka, Noushin Nabavi, Amir Reza Aref, Milad Ashrafizadeh, Haroon Khan, Masoud Najafi

2021Pharmacological Research136 citationsDOI

Topics & Concepts

Oxidative stressSuperoxide dismutaseReactive oxygen speciesPharmacologyTranscription factorCisplatinSignal transductionProgrammed cell deathCatalaseCancer researchGlutathione peroxidaseChemistryBiologyCell biologyApoptosisChemotherapyBiochemistryGeneGeneticsGenomics, phytochemicals, and oxidative stressChemotherapy-induced organ toxicity mitigationGlutathione Transferases and Polymorphisms
Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance | Litcius