Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors
Giovanna Delogu, Amit Kumar, Gianluca Gatto, Fernando Bustelo, Lucía M. Saavedra, Marı́a Isabel Rodrı́guez-Franco, Reyes Laguna, Dolores Viña
Topics & Concepts
ChemistryBenzofuranMoietyStereochemistryMonoamine oxidaseNitroRing (chemistry)Docking (animal)IC50Enzyme inhibitorEnzymeIn vitroBiochemistryOrganic chemistryAlkylNursingMedicineParkinson's Disease Mechanisms and TreatmentsCholinesterase and Neurodegenerative DiseasesBiochemical and biochemical processes