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The Effects of Autonomic Dysfunction on Functional Outcomes in Patients with Acute Stroke

Kyoung-Hyeon Cha, Nae Yoon Kang, Sungchul Huh, Sung‐Hwa Ko, Yong‐Il Shin, Ji Hong Min

2023Brain Sciences12 citationsDOIOpen Access PDF

Abstract

Autonomic dysfunction is a common complication of acute stroke, which impairs functional outcomes and increases mortality. There is a lack of well-established knowledge regarding the influence of autonomic dysfunction in patients with acute stroke. This study aims to investigate the impact of the severity of autonomic dysfunction on functional outcomes in patients with acute stroke. A retrospective analysis was conducted at a single center, involving 22 patients diagnosed with acute stroke. The severity of autonomic dysfunction was evaluated based on the Composite Autonomic Scoring Scale (CASS). The modified Barthel Index, Berg Balance Scale, Functional Ambulatory Category, and modified Rankin Scale were designated as functional outcome measures. The impact of the severity of autonomic dysfunction on functional outcomes was analyzed using one-way analysis of covariance (ANCOVA). A statistically significant difference was observed between the initial and follow-up functional outcomes based on the severity of autonomic dysfunction. This study presents evidence that the severity of autonomic dysfunction influences functional prognosis in patients with acute stroke. The findings will serve as additional considerations for the rehabilitation of patients with acute stroke.

Topics & Concepts

MedicineStroke (engine)Modified Rankin ScaleBerg Balance ScaleRehabilitationBalance (ability)Physical therapyAcute strokePhysical medicine and rehabilitationInternal medicineCardiologyIschemic strokeEngineeringMechanical engineeringTissue plasminogen activatorIschemiaHeart Rate Variability and Autonomic ControlAcute Ischemic Stroke ManagementFunctional Brain Connectivity Studies
The Effects of Autonomic Dysfunction on Functional Outcomes in Patients with Acute Stroke | Litcius