A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of living stem cell functions according to intracellular temperature
Hiroshi Yukawa, Masazumi Fujiwara, Kaori Kobayashi, Yuka Kumon, Kazu Miyaji, Yushi Nishimura, Keisuke Oshimi, Yumi Umehara, Yoshio Teki, Takayuki Iwasaki, Mutsuko Hatano, Hideki Hashimoto, Yoshinobu Baba
Abstract
, thus the intracellular temperature of living ASCs during several days of culturing could be precisely measured using the QTAS. Moreover, the intracellular temperature was found to influence the production of growth factors and the degree of differentiation into adipocytes and osteocytes. These data suggest that the QTAS can be used to investigate the relationship between intracellular temperature and cellular functions.
Topics & Concepts
IntracellularIncubationBiophysicsFluorescenceChemistryStem cellMaterials scienceCell biologyBiologyBiochemistryOpticsPhysicsDiamond and Carbon-based Materials ResearchCarbon Nanotubes in Compositesthermodynamics and calorimetric analyses