Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production
Ummey Khalecha Bintha Ahmed, Tyler M. Shadid, Jason L. Larabee, Jimmy D. Ballard
Abstract
C. difficile is a spore-forming, toxigenic, anaerobic bacterium that causes severe gastrointestinal illness. Understanding the ways in which C. difficile senses growth conditions to regulate toxin expression and sporulation is essential to advancing our understanding of this pathogen.
Topics & Concepts
ClostridioidesToxinMicrobiologyMotilityPathogenSporeBiologyClostridium difficile toxin ABacteriaClostridium difficileCell biologyGeneticsAntibioticsClostridium difficile and Clostridium perfringens researchGut microbiota and healthPharmacological Effects of Natural Compounds