Nuclear respiratory factor-1 (NRF1) induction drives mitochondrial biogenesis and attenuates amyloid beta-induced mitochondrial dysfunction and neurotoxicity
Matteo Massaro, Gherardo Baudo, Hyun-Ho Lee, Haoran Liu, Elvin Blanco
Abstract
-associated mitochondrial dysfunction and neurodegenerative cell processes, opening avenues for innovative therapeutic approaches aimed at safeguarding mitochondrial health in AD neurons.
Topics & Concepts
NRF1NeurotoxicityMitochondrial biogenesisMitochondrionBETA (programming language)TFAMNeuroscienceMitochondrial toxicityMedicineBiologyCell biologyInternal medicineToxicityComputer scienceProgramming languageMitochondrial Function and PathologyAlzheimer's disease research and treatmentsTryptophan and brain disorders