Ultrasensitive Detection of Ribonucleic Acid Biomarkers Using Portable Sensing Platforms Based on Organic Electrochemical Transistors
Ying Fu, Naixiang Wang, Anneng Yang, Zhiai Xu, Wen Zhang, Hong Liu, Hkw Law, Feng Yan
Abstract
M. The devices can distinguish blood miRNA expression levels at different cancer stages using a 4T1 mouse tumor model. The technique for ultrasensitive and fast detection of RNA biomarkers with high selectivity opens a window for mobile diagnosis of various diseases with low cost.
Topics & Concepts
ChemistryRNAmicroRNABiosensorNanotechnologyBiomarkerTransistorComputational biologyBiochemistryGeneMaterials scienceBiologyPhysicsVoltageQuantum mechanicsConducting polymers and applicationsAdvanced biosensing and bioanalysis techniquesAnalytical Chemistry and Sensors