Nondigestible carbohydrates and gut microbiota: A dynamic duo in host defense
Xin Zong, Shiqi Luo, Shuqi Liu, Edward C. Deehan, Yizhen Wang, Mingliang Jin
Abstract
Abstract The sophisticated relationship between the intake of dietary carbohydrates and host immunity is mediated in large part by the gut microbiota. This comprehensive review explores the multifaceted connections linking human gut microbiota with nondigestible carbohydrate metabolism and immune responses, highlighting the critical importance of this symbiotic relationship in maintaining overall host health. Understanding the mechanisms by which gut microbiota act as a bridge between carbohydrate intake and host immunity has significant implications for precision nutrition strategies and the development of therapeutic interventions.
Topics & Concepts
Gut floraHost (biology)BiologyMicrobiologyEcologyImmunologyGut microbiota and healthDiet and metabolism studiesClostridium difficile and Clostridium perfringens research