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Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

Elizabeth Culp, Nicholas Waglechner, Wenliang Wang, Aline Fiebig‐Comyn, Yen‐Pang Hsu, Kalinka Koteva, David Sychantha, Brian K. Coombes, Michael S. Van Nieuwenhze, Yves V. Brun, Gerard D. Wright

2020Nature299 citationsDOI

Topics & Concepts

PeptidoglycanGlycopeptideAntibioticsBiologyGeneAntibiotic resistanceMicrobiologyComputational biologyBacteriaPrioritizationGenomeGeneticsEconomicsManagement scienceMicrobial Natural Products and BiosynthesisGenomics and Phylogenetic StudiesBiochemical and Structural Characterization
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling | Litcius