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Cancer Detection in Breast MRI Screening via Explainable AI Anomaly Detection

Felipe Oviedo, Anum S. Kazerouni, Philipp Liznerski, Yixi Xu, Michael Hirano, Robert A. Vandermeulen, Marius Kloft, Elyse Blum, Adam Alessio, Christopher I. Li, William B. Weeks, Rahul Dodhia, Juan Lavista Ferres, Habib Rahbar, Savannah C. Partridge

2025Radiology13 citationsDOIOpen Access PDF

Abstract

An anomaly detection model for breast cancer on MRI scans achieved high performance, surpassing binary classification in high- and low-cancer-prevalence scenarios and producing explanation heat maps not significantly different from radiologist annotations.

Topics & Concepts

MedicineBreast cancerAnomaly (physics)CancerCancer detectionAnomaly detectionRadiologyMammographyArtificial intelligenceInternal medicineComputer sciencePhysicsCondensed matter physicsAI in cancer detectionRadiomics and Machine Learning in Medical ImagingAnomaly Detection Techniques and Applications
Cancer Detection in Breast MRI Screening via Explainable AI Anomaly Detection | Litcius