Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens
Yosra A. Helmy, Gary Closs, Kwonil Jung, Dipak Kathayat, Anastasia N. Vlasova, Gireesh Rajashekara
Abstract
specific and total IgA and IgY antibodies in chicken's serum. Microencapsulated EcN induced the expression of several cytokines and chemokines (1.6 to 4.3-fold), which activate the Th1, Th2, and Th17 pathways. Overall, microencapsulated EcN displayed promising effects as a potential nonantibiotic strategy to control C. jejuni colonization in chickens. Future studies on testing microencapsulated EcN in the feed and water of chickens raised on built-up floor litter would facilitate the development of EcN for industrial applications to control Campylobacter infections in poultry.
Topics & Concepts
Campylobacter jejuniBiologyProbioticMicrobiologyImmune systemAntibioticsCampylobacterGut floraBacteriaImmunologyGeneticsAnimal Nutrition and PhysiologyMoringa oleifera research and applicationsSalmonella and Campylobacter epidemiology