Melatonin Alleviates the Oxygen–Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2 (NFE2L2)/ROS/NLRP3 Pathway
Yu Zheng, Na Gao, Weixun Zhang, Rui Ma, Fanglu Chi, Zhen Gao, Ning Cong
Topics & Concepts
MelatoninHair cellPyroptosisLuzindoleOrgan of CortiReactive oxygen speciesMelatonin receptorOtotoxicityCell biologyReperfusion injuryIschemiaChemistryPharmacologyProgrammed cell deathBiologyInternal medicineApoptosisEndocrinologyMedicineCochleaNeuroscienceBiochemistryCisplatinChemotherapyInflammasome and immune disordersHearing, Cochlea, Tinnitus, GeneticsVestibular and auditory disorders