Sex Differences in Susceptibility to Coccidioidomycosis
Ian McHardy, Krystle L. Reagan, Jamie Sebastian, Bridget M. Barker, Derek J. Bays, Satya Dandekar, Stuart H. Cohen, Kathleen E Jennings, Jane E. Sykes, George R. Thompson
Abstract
To assess sex-specific differences in coccidioidomycosis, a retrospective analysis of human patients, nonhuman primates, and veterinary patients (including the neutered status of the animal) was performed. We found higher rates of infection and severity in males. This observed increased infection risk suggests deeper biological underpinnings than solely occupational/exposure risks.
Topics & Concepts
MedicineRetrospective cohort studyInternal medicineFungal Infections and StudiesNail Diseases and TreatmentsT-cell and Retrovirus Studies