Litcius/Paper detail

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman, Nicholas A. Eleuteri, Debabrata Bhunia, SeongShick Ryu, Li Tan, Kun Shi, Hong Yue, Xiaoxi Liu, Dennis Dobrovolsky, Baishan Jiang, Jinhua Wang, Mingfeng Hao, Inchul You, Mingxing Teng, Yanke Liang, John M. Hatcher, Zhengnian Li, Theresa Manz, Brian J. Groendyke, Wanyi Hu, Yunju Nam, Sandip Sengupta, Hanna Cho, Injae Shin, Michael P. Agius, Irene M. Ghobrial, W Michelle, Jianwei Che, Sara J. Buhrlage, Taebo Sim, Nathanael S. Gray, Eric S. Fischer

2020Cell372 citationsDOIOpen Access PDF

Topics & Concepts

KinomeBiologyComputational biologyDrug discoveryUbiquitinKinaseDrug developmentExpansiveProteasomeProteomicsBioinformaticsGeneDrugCell biologyBiochemistryPharmacologyMaterials scienceComposite materialCompressive strengthProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research