Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman, Nicholas A. Eleuteri, Debabrata Bhunia, SeongShick Ryu, Li Tan, Kun Shi, Hong Yue, Xiaoxi Liu, Dennis Dobrovolsky, Baishan Jiang, Jinhua Wang, Mingfeng Hao, Inchul You, Mingxing Teng, Yanke Liang, John M. Hatcher, Zhengnian Li, Theresa Manz, Brian J. Groendyke, Wanyi Hu, Yunju Nam, Sandip Sengupta, Hanna Cho, Injae Shin, Michael P. Agius, Irene M. Ghobrial, W Michelle, Jianwei Che, Sara J. Buhrlage, Taebo Sim, Nathanael S. Gray, Eric S. Fischer
Topics & Concepts
KinomeBiologyComputational biologyDrug discoveryUbiquitinKinaseDrug developmentExpansiveProteasomeProteomicsBioinformaticsGeneDrugCell biologyBiochemistryPharmacologyMaterials scienceComposite materialCompressive strengthProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research