Cryo-EM structures of the active NLRP3 inflammasome disc
Le Xiao, Venkat Giri Magupalli, Hao Wu
Topics & Concepts
InflammasomePyrin domainCell biologyInnate immune systemStructural biologySignal transducing adaptor proteinChemistryProtein subunitCytosolAutophagyBiophysicsBiologyBiochemistrySignal transductionApoptosisReceptorGeneEnzymeInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxideinterferon and immune responses