Recombinant Bacteriophage Cell-Binding Domain Proteins for Broad-Spectrum Recognition of Methicillin-Resistant <i>Staphylococcus aureus</i> Strains
Yingran Wang, Yong He, Sanjib Bhattacharyya, Shuguang Lu, Zhifeng Fu
Abstract
strains and other bacterial species. The recombinant CBD proteins were also successfully employed in antibiotic susceptibility testing of MRSA with a microplate-based method. The obtained results were consistent with those by the standard broth microdilution method. The satisfying results demonstrated their great application potential in clinical diagnosis and treatment of MRSA-induced infections.
Topics & Concepts
Staphylococcus aureusBacteriophageRecombinant DNAMicrobiologyLytic cycleMethicillin-resistant Staphylococcus aureusChemistryBacteriaVirologyBiologyEscherichia coliVirusGeneBiochemistryGeneticsBacteriophages and microbial interactionsAntimicrobial Resistance in StaphylococcusBacterial Identification and Susceptibility Testing