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A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity

Séan Mc Cafferty, A.K.M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee, Magalie Plovyt, Magdalena Stuchlíková, Nathalie R. Le François, Sophie Valembois, Leo Heyndríckx, Johan Míchiels, Kevin K. Ariën, Linos Vandekerckhove, Rana Abdelnabi, Caroline S. Foo, Johan Neyts, Itishri Sahu, Niek N. Sanders

2022Molecular Therapy56 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemAntigenVirologyBiologyAntibodyImmunityImmunologyHumoral immunityNeutralizing antibodyT cellVaccinationCD8SARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyViral Infections and Immunology Research
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity | Litcius