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In-depth characterization of a cysteine-linked ADC disitamab vedotin by multiple LC-MS analysis methods and cutting-edge imaged capillary isoelectric focusing coupled with native mass spectrometry

Gang Wu, Xiaoxi Zhang, Xin Wang, Jialiang Du, Meng Li, Gangling Xu, Min Du, Chuanfei Yu

2024Journal of Chromatography A11 citationsDOI

Topics & Concepts

ChemistryChromatographyMass spectrometryCysteineTandem mass spectrometryIsoelectric focusingHydrophilic interaction chromatographyHigh-performance liquid chromatographyBiochemistryEnzymeMonoclonal and Polyclonal Antibodies ResearchHER2/EGFR in Cancer ResearchCell Adhesion Molecules Research
In-depth characterization of a cysteine-linked ADC disitamab vedotin by multiple LC-MS analysis methods and cutting-edge imaged capillary isoelectric focusing coupled with native mass spectrometry | Litcius