Voluntary Inhibitory Control of Chorea: A Case Series
Roberta Bonomo, Anna Latorre, Bettina Balint, Katarzyna Śmiłowska, Lorenzo Rocchi, John C. Rothwell, Mario Zappia, Kailash P. Bhatia
Abstract
BACKGROUND: Volitional control of involuntary movements has so far been considered a hallmark of tic disorders. However, modulation of involuntary movements can also be observed in other hyperkinesias. CASES: Here, we present 6 patients with chorea able to suppress their involuntary movements, on demand. In 3 of them, surface electromyography was used to quantify degree of suppression and confirmed a reduction of muscle activity up to 68%, during volitional control. CONCLUSION: This observation represents a first step toward a description of a new clinical feature in choreic syndromes and an opportunity to redefine the role of volitional inhibition in hyperkinetic movement disorders.