Surface engineered iron oxide nanozyme for synergistic chemodynamic/photodynamic therapy with glutathione depletion and hypoxia relief
Muyao Li, Linlin Huo, Jie Zeng, Guifen Zhu, Saige Shi, Xiangqing Liu, Xianglong Zhu, Guoming Huang, Dachuan Qiu, Jian‐Hua Jia, Kaiyuan Ni, Zhenghuan Zhao
Topics & Concepts
Reactive oxygen speciesGlutathionePhotodynamic therapyChemistryTumor hypoxiaTumor microenvironmentHydrogen peroxideGlutathione peroxidaseIn vivoHypoxia (environmental)CatalaseGPX4Cancer researchRadicalBiophysicsBiochemistryOxygenOxidative stressEnzymeRadiation therapyMedicineTumor cellsInternal medicineBiologyBiotechnologyOrganic chemistryNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisExtracellular vesicles in disease