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A hybrid framework of artificial intelligence-based neural network model (ANN) and central composite design (CCD) in quality by design formulation development of orodispersible moxifloxacin tablets: Physicochemical evaluation, compaction analysis, and its in-silico PBPK modeling

Momina Zarish Khan, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Farrukh Rafiq Ahmed, Muhammad Talha Saleem, Fahad Siddiqui, Syed Adnan Rizvi

2023Journal of Drug Delivery Science and Technology14 citationsDOI

Topics & Concepts

Quality by DesignCentral composite designArtificial neural networkDesign of experimentsComputer scienceMultilayer perceptronMachine learningMathematicsResponse surface methodologyEngineeringStatisticsDownstream (manufacturing)Operations managementDrug Solubulity and Delivery SystemsAnalytical Methods in PharmaceuticalsComputational Drug Discovery Methods
A hybrid framework of artificial intelligence-based neural network model (ANN) and central composite design (CCD) in quality by design formulation development of orodispersible moxifloxacin tablets: Physicochemical evaluation, compaction analysis, and its in-silico PBPK modeling | Litcius