Nonenzymatic Electrochemical Sensor for Wearable Interstitial Fluid Glucose Monitoring
Lanjie Lei, Chao Zhao, Xiaofei Zhu, Shuai Yuan, Xing Dong, Yinxiu Zuo, Hong Liu
Abstract
Abstract We report on a nonenzymatic electrochemical sensor for wearable glucose monitoring in interstitial fluid. The sensor exhibited acceptable selectivity and reliability for continuous glucose detection for up to 30 days. The sensor tip is coated with polyurethane, and the biocompatibility of the tip is investigated by tissue staining. A fully integrated wearable glucose monitoring system is developed with a wireless connection with a smartphone. The test results are in agreement with reference methods. So, we believe the sensor is promising for the development of a continuous glucose monitoring system and diabetes management.
Topics & Concepts
Wearable computerElectrochemical gas sensorContinuous glucose monitoringBiocompatibilityContinuous monitoringMaterials scienceBiomedical engineeringBlood Glucose Self-MonitoringElectrochemistryNanotechnologyComputer scienceEmbedded systemChemistryElectrodeDiabetes mellitusMedicineEngineeringGlycemicEndocrinologyMetallurgyPhysical chemistryOperations managementElectrochemical sensors and biosensorsAdvanced Sensor and Energy Harvesting MaterialsConducting polymers and applications