Hepatocyte proliferation activity in untreated rats, measured by immunohistochemical detection of Ki-67: The effect of age on the repeated-dose liver micronucleus assay
Kensuke Satomoto, Moeko Aoki, Atsushi Wakita, Hiroshi Yamagata, Tatsuya Mitsumoto, Takezo Okamoto, Ryoko Harada, Shuichi Hamada
Topics & Concepts
DosingHepatocyteImmunohistochemistryMedicineInternal medicineAndrologyEndocrinologyMicronucleusToxicityRegimenPharmacologyBiologyMicronucleus testIn vitroBiochemistryCarcinogens and Genotoxicity AssessmentDrug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism