Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control
Yang Hu, Alejandra Korovaichuk, Mariana Astiz, Henning Schroeder, Rezaul Islam, Jon Jatsu Azkue, André Fischer, Henrik Oster, Henrik Bringmann
Abstract
genes functionally diversified to allow for a bidirectional control of sleep quality. Divergence of AP-2 transcription factors might perhaps have supported the evolution of more complex types of sleep.
Topics & Concepts
BiologyGeneticsFunctional divergenceTranscription factorTranscription (linguistics)GeneDivergence (linguistics)Control (management)Sleep (system call)Evolutionary biologyComputational biologyGene expressionComputer scienceGene familyArtificial intelligenceLinguisticsPhilosophyOperating systemSleep and Wakefulness ResearchCircadian rhythm and melatoninGenetics and Neurodevelopmental Disorders