Targeted truncated TGF-β receptor type II delivery to fibrotic liver by PDGFβ receptor-binding peptide modification for improving the anti-fibrotic activity against hepatic fibrosis in vitro and in vivo
Zhen Huang, Minglu Ding, Yixin Dong, Manman Ma, Xudong Song, Yong Liu, Zhihan Gao, Huilin Guan, Yanhui Chu, Feng Hua, Xiaohua Wang, Haifeng Liu
Topics & Concepts
Hepatic stellate cellFibrosisHepatic fibrosisTransforming growth factorReceptorCancer researchIn vivoGrowth factorPlatelet-derived growth factor receptorBiologyPathologyMedicineEndocrinologyBiochemistryBiotechnologyLiver physiology and pathologyLiver Disease Diagnosis and TreatmentLiver Diseases and Immunity