Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
Susan Kelso, Siobhan O’Brien, Igor Kurinov, Stéphane Angers, Frank Sicheri
Topics & Concepts
Isothermal titration calorimetryCyclin-dependent kinaseKinaseBiologyCell biologyRNA splicingCell cycleBiochemistryRNACellGeneMicrotubule and mitosis dynamicsUbiquitin and proteasome pathwaysCancer-related Molecular Pathways