Copper-catalyzed functionalization/transformation of styrenes with polyhaloalkanes and arenes enables the synthesis of heteroarene-containing <i>gem</i>-dihaloalkenes
Yilin Zhao, Yong Yao, Wanting Li, Jing‐Hao Qin, Qing Sun, Jin‐Heng Li, Xuan‐Hui Ouyang
Abstract
A new copper-catalyzed three-component functionalization/transformation of styrenes using polyhaloalkanes and arenes is disclosed, allowing the synthesis of versatile functionalized heteroarene-containing gem -dihaloalkenes.
Topics & Concepts
ChemistrySurface modificationCopperCatalysisCombinatorial chemistryTransformation (genetics)Organic chemistryPolymer chemistryPhysical chemistryBiochemistryGeneFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms