TREM2 mitigates NLRP3-mediated neuroinflammation through the NF-κB and PI3k/Akt signaling pathways in juvenile rats exposed to ambient particulate matter
Jianxiong Gui, Jie Liu, Lingman Wang, Hanyu Luo, Dishu Huang, Xiaoyue Yang, Honghong Song, Ziyao Han, Ran Ding, Jiaxin Yang, Li Jiang
Topics & Concepts
NeuroinflammationInflammasomePI3K/AKT/mTOR pathwayProtein kinase BTREM2ChemistrySignal transductionNF-κBCell biologyMicrogliaPharmacologyInflammationReceptorBiologyImmunologyBiochemistryInflammation biomarkers and pathwaysNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders