A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
Yongliang Tong, Runqiu Chen, Xinrong Lu, Cuiying Chen, Gui-qin Sun, Xiaolu Yu, Shaoxian Lyu, Meiqing Feng, Yiru Long, Likun Gong, Li Chen
Topics & Concepts
Sialic acidChemistryLectinFusion proteinEnzymeC-type lectinCancer researchBiochemistryMolecular biologyBiologyGeneRecombinant DNAMonoclonal and Polyclonal Antibodies ResearchGalectins and Cancer BiologyGlycosylation and Glycoproteins Research