Dysbiosis of Gut Microbiota and Intestinal Barrier Dysfunction in Pigs with Pulmonary Inflammation Induced by Mycoplasma hyorhinis Infection
Yingying Zhang, Yuan Gan, Jia Wang, Zhixin Feng, Zhaoxin Zhong, Hongduo Bao, Qiyan Xiong, Ran Wang
Abstract
Cumulative evidence suggests that bacterial pneumonia may contribute to the dysbiosis of the gut microbiota and other gastrointestinal symptoms. Our experiment has demonstrated that lung inflammation induced by M. hyorhinis infection was associated with gut microbiota dysbiosis and intestinal barrier dysfunction, which may provide a theoretical basis for exploring the gut-lung axis based on M. hyorhinis infection.
Topics & Concepts
DysbiosisInflammationBarrier functionBiologyGut floraImmunologyLungProinflammatory cytokineDiamine oxidaseMicrobiologyMedicineInternal medicineEnzymeCell biologyBiochemistryGut microbiota and healthMicrobial infections and disease researchMycobacterium research and diagnosis