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Extracellular Vesicles Released by <i>Lactobacillus paracasei</i> Mitigate Stress-induced Transcriptional Changes and Depression-like Behavior in Mice

Hye‐Jin Kwon, Eun Hwa Lee, Juli Choi, Jin‐Young Park, Yoon‐Keun Kim, Pyung‐Lim Han

2023Experimental Neurobiology13 citationsDOIOpen Access PDF

Abstract

-EV cargo contains bioactive components that directly induce genome-wide transcriptional responses against GC-induced transcriptional and behavioral changes.

Topics & Concepts

GeneBiologyFKBP5Microarray analysis techniquesMicroarrayHistoneCell biologyGenomeExtracellularGene expressionChemistryGeneticsGlucocorticoid receptorAntimicrobial Peptides and ActivitiesGut microbiota and healthExtracellular vesicles in disease