LARS1 lactylation inhibits autophagy by activating mTORC1 to promote podocytes injury in diabetic kidney disease
Zhibin Fan, Yue Zhang, Liming Yuan, Yuan Gao, Xiaoxi Tian, Jin Tian, Jie Wan, Bingyu Li, Xiao-Qi Wang, Shuo Wang, Lianshan Zhang, Lei Wang, Pengxiang Zhou, Wei Liu
Topics & Concepts
AutophagymTORC1PodocyteDiabetic nephropathyDiseaseKidney diseaseMedicineCell biologyKidneyRenal injuryCancer researchPI3K/AKT/mTOR pathwayPharmacologyBiologyEndocrinologyInternal medicineSignal transductionApoptosisBiochemistryProteinuriaRenal Diseases and GlomerulopathiesGenetic and Kidney Cyst DiseasesChronic Kidney Disease and Diabetes