Convergent and Divergent Age Patterning of Gut Microbiota Diversity in Humans and Nonhuman Primates
Jianan Sang, Daohua Zhuang, Tao Zhang, Qunfu Wu, Jiangkun Yu, Zhigang Zhang
Abstract
This study provides the first comprehensive investigation of age patterning of gut microbiota of four human populations and three nonhuman primates and found that Prevotellamassilia , Prevotella , Gemmiger , Coprococcus , Faecalibacterium , and Roseburia may be common antiaging microbial markers in both humans and nonhuman primates due to their potential metabolic capabilities for host health benefits. Our results also provide key support for using macaques as animal models in studies of the gut microbiome’s role during human aging.
Topics & Concepts
BiologyPrevotellaMicrobiomeGut floraZoologyCommensalismBacteriaGeneticsImmunologyGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders