Reduction-responsive disulfide linkage core-cross-linked polymeric micelles for site-specific drug delivery

Gaizhen Kuang, Qingfei Zhang, Shasha He, Yanjuan Wu, Yubin Huang

2020Polymer Chemistry28 citationsDOI

Abstract

Reduction-responsive disulfide linkage core-cross-linked polymeric micelles (CLM@DOX) were developed for effective site-specific doxorubicin delivery.

Topics & Concepts

Disulfide LinkageMicelleLinkage (software)Disulfide bondChemistryDoxorubicinDrug deliveryCombinatorial chemistryReduction (mathematics)BiochemistryOrganic chemistryAqueous solutionChemotherapyCysteineBiologyGeneticsGeneMathematicsGeometryEnzymeNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsDendrimers and Hyperbranched Polymers