Expeditious access of chromone analogues <i>via</i> a Michael addition-driven multicomponent reaction
Jie Lei, Yong Li, Liu‐Jun He, Yafei Luo, Dianyong Tang, Wei Yan, Hui-Kuan Lin, Hongyu Li, Zhong‐Zhu Chen, Zhigang Xu
Abstract
A Michael addition-driven four-component reaction (4-CR) with four Ugi inputs was developed and utilized for the synthesis of chromone derivatives and tetrazole substituted chromones under mild reaction conditions.
Topics & Concepts
ChromoneChemistryMichael reactionTetrazoleCombinatorial chemistryAddition reactionOrganic chemistryCatalysisMulticomponent Synthesis of HeterocyclesSynthesis of Organic CompoundsSynthesis and biological activity