Light-Induced Anti-Bacterial Effect Against <i>Staphylococcus aureus</i> of Porphyrin Covalently Bonded to a Polyethylene Terephthalate Surface
Stefania F. Musolino, Fatima Shatila, Grace M.O. Tieman, Anna C. Masarsky, Matthew C. Thibodeau, Jeremy E. Wulff, Heather L. Buckley
Abstract
was determined qualitatively and quantitatively. The growth of the pathogen beneath porphyrin-functionalized PET coupons was reduced; moreover, the PET coupons resulted in a 1.76-log reduction in cell counts after exposure to white LED light for 6 h. This is a promising material and platform for the development of safer antimicrobial surfaces, with applications in healthcare, food packaging, marine surfaces, and other surfaces in the environment.
Topics & Concepts
PorphyrinPolyethylene terephthalateCovalent bondStaphylococcus aureusPolyethyleneMaterials scienceChemistryMicrobiologyComposite materialPhotochemistryBacteriaOrganic chemistryBiologyGeneticsPhotodynamic Therapy Research StudiesWater Treatment and DisinfectionAntimicrobial agents and applications